Buy THJ-2201 crystal
It is a structural analog of AM-2201 in which the central indole ring has been replaced by indazole.
Summary sheet: THJ-2201
THJ-2201 (1-[(5-fluoropentyl)-1H-indazol-3-yl](naphthalen-1-yl)methanone) is a synthetic cannabinoid and analog of AM-2201. It has been marketed by many research chemical vendors as a legal alternative to the popular AM-2201, which had been banned in 2011.
Cannabinoids are commonly smoked or vaporized to achieve a quick onset of effects and rapid offset. THJ-2201 is orally active when dissolved in a lipid, which can increase the duration significantly. Like other cannabinoids, it is insoluble in water but dissolves in ethanol and lipids.
Unlike cannabis, the chronic abuse of synthetic cannabinoids has been associated with multiple deaths and more dangerous side effects and toxicity in general. Therefore, it is strongly discouraged to take this substance for extended periods of time or in excessive doses.
Although this substance has not been formally studied, from analysis of the structure, it is presumed that THJ-2201 has a similar binding profile to that of AM-2201 and matches many of the in vivo properties of Δ9-THC. As with AM-2201, this compound is believed to act as a potent full agonist to the central CB1 and peripheral CB2 receptors with Ki values of 1.0 and 2.6nM respectively. However, the role of these interactions and how they result in the cannabinoid high experience continues to remain elusive.
The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. These effects should be taken with a grain of salt and will rarely (if ever) occur all at once, but heavier doses will increase the chances of inducing a full range of effects. Likewise, adverse effects become much more likely on higher doses and may include serious injury or death.
Chemical and physical data
Molar mass 360.42 g/mol g·mol−1
3D model (JSmol) Interactive
List of AM cannabinoids
List of JWH cannabinoids